A Fast and Reliable Computational Method for Estimating Population Genetic Parameters
نویسندگان
چکیده
منابع مشابه
A fast and reliable computational method for estimating population genetic parameters.
The estimation of ancestral and current effective population sizes in expanding populations is a fundamental problem in population genetics. Recently it has become possible to scan entire genomes of several individuals within a population. These genomic data sets can be used to estimate basic population parameters such as the effective population size and population growth rate. Full-data-likel...
متن کاملLeoTask: a fast, flexible and reliable framework for computational research
Summary: LeoTask is a Java library for computation-intensive and time-consuming research tasks. It automatically executes tasks in parallel on multiple CPU cores on a computing facility. It uses a configuration file to enable automatic exploration of parameter space and flexible aggregation of results, and therefore allows researchers to focus on programming the key logic of a computing task. I...
متن کاملA simple and reliable method for estimating haemoglobin.
A new colour scale has been advised for estimating haemoglobin levels by matching the blood samples with ten levels of haemoglobin (3, 4, 5, 6, 7, 8, 9, 10, 12, and 14 g/dl) on the scale. Preliminary results show good correlations with spectrophotometric readings. The new device is being field tested and if the initial promise is confirmed, will provide a simple and reliable method for estimati...
متن کاملEstimating ancestral population parameters.
The expected numbers of different categories of polymorphic sites are derived for two related models of population history the isolation model, in which an ancestral population splits into two descendents, and the size-change model, in which a single population undergoes an instantaneous change in size. For the isolation model, the observed numbers of shared, fixed, and exclusive polymorphic si...
متن کاملA Genetic Algorithm Based Augmented Lagrangian Method for Accurate, Fast and Reliable Constrained Optimization
Among the penalty based approaches for constrained optimization, augmented Lagrangian (AL) methods are better in at least three ways: (i) they have theoretical convergence properties, (ii) they distort the original objective function minimally, thereby providing a better function landscape for search, and (iii) they can result in computing optimal Lagrange multiplier for each constraint as a by...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genetics
سال: 2008
ISSN: 1943-2631
DOI: 10.1534/genetics.108.087049